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學術研究成果

歷年發表與研究計畫

論文發表及著作

  1. Shao-Hsuan Chang, Chung-Pei Ma, Kuo-Hsuan Hung, I-Ming Chang, Hsieh-Fu Tsai, Lung-Kun Yeh. Transcriptomic Signatures and miRNA-mRNA Regulatory Networks in Keratoconus Identified by Multi-cohort Profiling​. 2025 (submitted)

  2. Chi-Sheng Chen and Shao-Hsuan Chang*. A Hybrid Quantum-Classical Approach to Vision Transformers: Introducing QASA-ViT for Efficient Image Recognition​. 2025 (submitted)  

  3. Chi-Sheng Chen, Wen-Yen Hsu, Tung-Ming Pan, Che-Wei Liu, Shao-Hsuan Chang*. A Quantum-Driven Multimodal Framework for EEG-Image Association: Integrating Hybrid Encoding and Contrastive Learning Approaches​. 2025 (Under review)  

  4. Shao-Hsuan Chang, Yu-Chen Huang, Che-Wei Liu. Effects of Beta-Blockers on Reoperation Rate and Surgical Comorbidities in Single Level Lumbar Spinal Fusion. 2025 (Under review) 

  5. Shao-Hsuan Chang, Siu-Ning Tsang, Yi-Chih Chen, Yu-Chen Huang, Che-Wei Liu. The Impact of Beta-Blocker Use on Fracture Healing and Nonunion Risk in Tibial and Femoral Fracture Patients: A Retrospective Analysis Using Real-World Data. 2025 (Under review) 

  6. Shao-Hsuan Chang, Ching-Mao Chang, Kae-Kuen Hu, Mei-Ching Yu, Lung-Kun Yeh. Health Motivation and mHealth Use in Adults With Varying BMI: A Cross-Sectional Survey. 2025 (revised) 

  7. Chi-Sheng Chen*, Shao-Hsuan Chang*, Che-Wei Liu, Tung-Ming Pan. Exploring the Potential of Electroencephalography Signal-Based Image Generation Using Diffusion Models: An Integrative Framework Combining Mixed Methods and Multimodal Analysis. JMIR Medical Informatics. 2025; DOI:10.2196/72027 (IF:3.8)

  8. Tung-Ming Pan, Hong-Yang Ding, Shao-Hsuan Chang, Jim-Long Her. High-performance pH Sensing with Spin-coated HfxZr1-xO2 Ceramic Films in Extended-gate Field-effect Transistors. Ceramics International 2025; DOI:10.1016/j.ceramint.2025.05.265 (IF:5.1)

  9. Shao-Hsuan Chang, Lung-Kun Yeh, Kuo-Hsuan Hung, Yen-Jung Chiu, Chia-Hsun Hsieh, Chung-Pei Ma. Machine Learning-Driven Transcriptome Analysis of Keratoconus for Predictive Biomarker Identification. Biomedicines. 2025;13(5);1032. DOI:10.3390/biomedicines13051032 (IF:4.1)

  10. Shao-Hsuan Chang, Hong-Yang Ding, Tung-Ming Pan. Structural and Sensing Properties of Hfxzr1-XO2 Films Prepared Through a Spin-Coating Sol-Gel Method for pH and Procalcitonin Detection. Talanta. 2025; DOI:10.1016/j.talanta.2025.128221 (IF:5.6)

  11. Shao-Hsuan Chang, Daishi Chen, Chi-Sheng Chen, Dong Zhou, Lung-Kun Yeh. Device Failures and Adverse Events Associated With Rhinolaryngoscopes: Analysis of the Manufacturer and User Facility Device Experience (MAUDE) Database. JMIR Hum Factors 2025;12:e67036. DOI: 10.2196/67036 (IF:3.0)

  12. Huei-Ying Li, Chun-Chuan Chang, Yu-Hsuan Yang, Chi-Yuan Yao, Jason Chia-Hsun Hsieh, Shao-Hsuan Chang*. The Prospects and Limitations of Liquid Biopsy Utilization for Clinical Practice in Taiwan. The Journal of Liquid Biopsy. 2025;7;100290. DOI:10.1016/j.jlb.2025.100290 (IF:0.0)

  13. Chi-Sheng Chen, Guan-Ying Chen, Dong Zhou, Di Jiang, Daishi Chen, Shao-Hsuan Chang*. Improving fine-grained food classification using deep residual learning and selective state space models. PLOS  ONE. 2025;20(5): e0322695. DOI:10.1371/journal.pone.0322695 (IF:3.2)

  14. Chi-Sheng Chen, Yu-Hsuan Yang, Guan-Ying Chen, Shao-Hsuan Chang*. Food Classification for Dietary Support Using Fine-Grained Visual Recognition with the HERBS Network.  2024;DOI:10.20944/preprints202410.2080.v1 

  15. Winston W Y Kao, Jianhua Zhang, Jhuwala Venkatakrishnan, Shao-Hsuan Chang, Yong Yuan, Osamu Yamanaka, Ying Xia, Tarsis F. Gesteira, Sudhir Verma, Vivien Coulson-Thomas, and Chia-Yang Liu. Lumican/Lumikine Promotes Healing of Corneal Epithelium Debridement by Upregulation of EGFR Ligand Expression via Noncanonical Smad-Independent TGFβ/TBRs Signaling. Cells 2024;DOI: 10.3390/cells13191599 (IF:6.0)

  16. Yi-Chun Su, Trinh T. T. Phan, Tzu-Wei Wang, Shao-Hsuan Chang, Feng-Huei Lin, Tzu-Sheng Hsu and Lih-Yuan Lin Nanoscaled Biphasic Calcium Phosphate Modulates Osteogenesis and Attenuates LPS-induced Inflammatory. Front Bioeng Biotechnol. 2023;DOI 10.3389/fbioe.2023.1236429 (IF:5.7)

  17. Shao-Hsuan Chang, Dong Zhou, Ashkan Eliasy, Yi-Chen Li, Ahmed Elsheikh. Experimental Evaluation of Stiffening Effect Induced by UVA/Riboflavin Corneal Cross-linking using Intact Porcine Eye Globes. PLOS ONE. 2020:15(11):e0240724 (IF:3.3)

  18. Shao-Hsuan Chang, Ashkan Mohammadvali, Kai-Jung Chen, You-Ren Ji, Tai-Horng Young, Tsung-Jen Wang, Colin E. Willoughby, Kevin J. Hamill, Ahmed Elsheikh. Determination of the Relationship Between Mechanical Properties, Ultrastructural Changes and Intrafibrillar Bond Formation in Corneal UVA/riboflavin Cross-linking Treatment for Keratoconus. Refract Surg. 2018;34:264-272 (IF:2.9)

  19. Yu-Hsin Wang, Shao-Hsuan Chang, Daxen Mau-Hsu, Jyh-Horng Wang, Tai-Horng Young. Poly (N-(4-aminobutyl)-acrylamide) as Mimetic Polylysine for Improving Survival and Differentiation of Cerebellar Granule Neurons. J Biomed Mater Res B Appl Biomater. 2017;DIO:10.1002/jbm.b.33932 (IF:3.1)

  20. Vivien Jane Coulson-Thomas, Shao-Hsuan Chang, Lung-Kun Yeh, Chang-Gung, Yu Yamaguchi, Jerrrey Esko, Chia-Yang Liu and Winston Kao. Loss of Corneal Epithelial Heparin Sulfate Leads to Corneal Degeneration and Impaired Wound Healing. IOVS. 2015;56:3004-3014 (IF:5.0)

  21. Yi-Hsin Chen, Shao-Hsuan Chang, I-Jong Wang, Tai-Horng Young. The Mechanism for Keratinocyte Detaching from pH-responsive Chitosan. Biomaterials. 2014;(35)9247-9254 (IF:12.5)

  22. Osamu Yamanaka, Yong Yuan, Vivien Jane Coulson-Thomas, Tarsis Ferreira Gesteira, Mindy K. Call, Yujin Zhang, Jianhua Zhang, Shao-Hsuan Chang, Chia-Yang Liu, Shizuya Saika, James V. Jester and Winston W-Y Kao. Lumican Binds ALK5 to Promote Epithelium Wound Healing. PLOS ONE. 2013;8(12):e82730 (IF:3.3)

  23. Shao-Hsuan Chang, I-Ni Chiang, Yi-Hsin Chen, Tai-Horng Young. Serum-free Culture of Rat Proximal Tubule Cells with Enhanced Function on Chitosan. Acta Biomaterialia. 2013;9:8942-8951 (IF:9.7)

  24. Yi-Hsin Chen, Shao-Hsuan Chang, Tsung-Jen Wang, I-Jong Wang, Tai-Horng Young. Cell Fractionation on pH-responsive Chitosan Surface. Biomaterials. 2013;34:854-863 (IF:12.5)

​1. 圓錐角膜基因分析 (國科會)

2. 生醫醫材類技術產創開發計畫暨SPARK (長庚大學) 

3. 雛型品計畫 (BMCC商品化中心)

4. 臨床試驗新型態卓越計畫 (衛生福利部)

5. 營養AI預測模型研發計畫 (產學合作)

6. 卓越低風險醫療器材安全品質計畫 (食品藥物管理署)

​7. 藥品與醫療器材新南向計畫 (食品藥物管理署)

研究計畫

聯絡我們:
Tel: (03) 211-8800  # 3080
Email: D000019876@cgu.edu.tw
長庚大學工學大樓四樓

桃園市龜山區文化一路259號

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工業技術研究院

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