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學術研究成果

歷年發表與研究計畫

論文發表及著作

  1. Shao-Hsuan Chang, Lung-Kun Yeh, Kuo-Hsuan Hung, Chung-Pei Ma*. Machine Learning-Driven Transcriptome Analysis of Keratoconus for Predictive Biomarker Identification. 2025 (under review)

  2. Shao-Hsuan Chang, Lung-Kun Yeh*, Kae-Kuen Hu, Mei-Ching Yu. The Impact of Digital Health: Motivation for Self-Management and The Use of mHealth Tools in Health Promotion. 2025 (under review)

  3. Chi-Sheng Chen, Shao-Hsuan Chang, Tung-Ming Pan*. Exploring the Potential of EEG Signal-based Image Generation with Diffusion Models: A New NEural-COgnitive MultImodal EEG-InforMed Image Generation with Diffusion Models (NECOMIMI) Framework. 2025 (under review)

  4. Chi-Sheng Chen, Guan-Ying Chen, Dong Zhou, Shao-Hsuan Chang*. Improving Fine-Grained Visual Classification using Deep Residual Learning and Selective State Space Models. PLOS ONE 2025 (accepted)

  5. Huei-Ying Li, Chun-Chuan Chang, Yu-Hsuan Yang, Chi-Yuan Yao, Jason Chia-Hsun Hsieh, Shao-Hsuan Chang*. The Prospects and Limitations of Liquid Biopsy Utilization for Clinical Practice in Taiwan. Journal of Liquid Biopsy. 2025;DOI:10.1016/j.jlb.2025.100290

  6. Chi-Sheng Chen, Yu-Hsuan Yang, Guan-Ying Chen, Shao-Hsuan Chang*. Food Classification for Dietary Support Using Fine-Grained Visual Recognition with the HERBS Network.  2024;DOI:10.20944/preprints202410.2080.v1 

  7. Winston W Y Kao*, Jianhua Zhang, Jhuwala Venkatakrishnan, Shao-Hsuan Chang, Yong Yuan, Osamu Yamanaka, Ying Xia, Tarsis F. Gesteira, Sudhir Verma, Vivien Coulson-Thomas, and Chia-Yang Liu. Lumican/Lumikine Promotes Healing of Corneal Epithelium Debridement by Upregulation of EGFR Ligand Expression via Noncanonical Smad-Independent TGFβ/TBRs Signaling. Cells 2024;DOI: 10.3390/cells13191599 2024 

  8. Yi-Chun Su, Trinh T. T. Phan, Tzu-Wei Wang, Shao-Hsuan Chang, Feng-Huei Lin, Tzu-Sheng Hsu* and Lih-Yuan Lin* Nanoscaled Biphasic Calcium Phosphate Modulates Osteogenesis and Attenuates LPS-induced Inflammatory. Front. Bioeng. Biotechnol. 2023;DOI 10.3389/fbioe.2023.1236429 

  9. Shao-Hsuan Chang, Dong Zhou, Ashkan Eliasy, Yi-Chen Li*, Ahmed Elsheikh. Experimental Evaluation of Stiffening Effect Induced by UVA/Riboflavin Corneal Cross-linking using Intact Porcine Eye Globes. PLOS ONE. 2020:15(11):e0240724 

  10. Shao-Hsuan Chang. The Comprehensive Insight of Interrelations between Mechanical, Biochemical and Structural Changes in Corneal UVA/riboflavin Cross-linking Treatment for Keratoconus. University of Liverpool. 2019

  11. Shao-Hsuan Chang, Ashkan Mohammadvali, Kai-Jung Chen, You-Ren Ji, Tai-Horng Young, Tsung-Jen Wang, Colin E. Willoughby, Kevin J. Hamill*, Ahmed Elsheikh. Determination of the Relationship Between Mechanical Properties, Ultrastructural Changes and Intrafibrillar Bond Formation in Corneal UVA/riboflavin Cross-linking Treatment for Keratoconus. Refract Surg. 2018;34:264-272

  12. Yu-Hsin Wang, Shao-Hsuan Chang, Daxen Mau-Hsu, Jyh-Horng Wang. Tai-Horng Young*. Poly (N-(4-aminobutyl)-acrylamide) as Mimetic Polylysine for Improving Survival and Differentiation of Cerebellar Granule Neurons. J Biomed Mater Res B Appl Biomater. 2017;DIO:10.1002/jbm.b.33932. 

  13. Vivien Jane Coulson-Thomas*, Shao-Hsuan Chang, Lung-Kun Yeh, Chang-Gung, Yu Yamaguchi, Jerrrey Esko, Chia-Yang Liu and Winston Kao. Loss of Corneal Epithelial Heparin Sulfate Leads to Corneal Degeneration and Impaired Wound Healing. IOVS. 2015;56:3004-3014 

  14. Yi-Hsin Chen, Shao-Hsuan Chang, I-Jong Wang, Tai-Horng Young*. The Mechanism for Keratinocyte Detaching from pH-responsive Chitosan. Biomaterials. 2014;(35)9247-9254 

  15. Osamu Yamanaka, Yong Yuan, Vivien Jane Coulson-Thomas, Tarsis Ferreira Gesteira, Mindy K. Call, Yujin Zhang, Jianhua Zhang, Shao-Hsuan Chang, Chia-Yang Liu, Shizuya Saika, James V. Jester and Winston W-Y Kao. Lumican Binds ALK5 to Promote Epithelium Wound Healing. PLOS ONE. 2013;8(12):e82730 

  16. Shao-Hsuan Chang, I-Ni Chiang, Yi-Hsin Chen, Tai-Horng Young*. Serum-free Culture of Rat Proximal Tubule Cells with Enhanced Function on Chitosan. Acta Biomaterialia. 2013;9:8942-8951. 

  17. Yi-Hsin Chen, Shao-Hsuan Chang, Tsung-Jen Wang, I-Jong Wang, Tai-Horng Young*. Cell Fractionation on pH-responsive Chitosan Surface. Biomaterials. 2013;34:854-863. 

​1. 雛型品計畫 (BMCC商品化中心)

2. 臨床試驗新型態卓越計畫 (衛生福利部)

2. 營養AI預測模型研發計畫 (產學合作)

3. 卓越低風險醫療器材安全品質計畫 (食品藥物管理署)

​4. 藥品與醫療器材新南向計畫 (食品藥物管理署)

研究計畫

聯絡我們:
Tel: (03) 211-8800  # 3080
Email: D000019876@cgu.edu.tw
長庚大學工學大樓四樓

桃園市龜山區文化一路259號

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